The New England Journal of Medicine (NEJM) RSS feed -- Search Results in NO TITLE. NEJM (https://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. https://www.nejm.org/action/showPodcastsFeeds NEJM Group Thu, 21 May 2026 16:39:25 GMT 2026 NEJM Group en-us 1440 Vaccine hesitancy is often driven by safety concerns. Clinician recommendations, presumptive communication, and empathy improve uptake; maintaining trust supports future acceptance and community protection. https://www.nejm.org/doi/full/10.1056/NEJMcp2516616?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcp2516616 Sean T. O’Leary, Margie Danchin 2026-05-20 Childhood Vaccine Hesitancy This Double Take video outlines the five risk factors for cardiovascular disease and reviews strategies for blood-pressure control to reduce morbidity and mortality. https://www.nejm.org/doi/full/10.1056/NEJMp2516850?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2516850 Holly Biola, Sadiya S. Khan, Donald Lloyd-Jones, Neha J. Pagidipati, Willie McDonald, Patrick G. O’Malley 2026-05-20 Double Take: Cardiovascular Risk Factors — Hypertension The Indian Health Pathway at the University of Washington School of Medicine aims to help bridge the health gap between Indigenous Americans and the broader U.S. population. https://www.nejm.org/doi/full/10.1056/NEJMp2605243?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2605243 Joseph Nelson, Millie Kennedy, Jason F. Deen 2026-05-20 Efforts toward Equity: Advancing Indigenous Health Equity in Medical School Curricula Many Black veterans live below the poverty line, often struggling to manage their illnesses. As V.A. hospitals began to stop using race-corrected interpretation of Black patients’ spirometer readings, there was an epiphany: the race correction wasn’t just harming the health of Black patients, it was also hurting them financially. https://www.nejm.org/doi/full/10.1056/NEJMp2601976?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2601976 2026-05-20 Intention to Treat — Season 2: The Race Equation: Money and Misdiagnosis — ITT Episode 2.3 On May 2, hantavirus infection was diagnosed in a patient who had been on a cruise ship. Subsequent evaluation revealed multiple cases of Andes hantavirus infection on the ship. To date, three associated deaths have occurred. https://www.nejm.org/doi/full/10.1056/NEJMc2606496?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2606496 Andes Virus Outbreak Working Group 2026-05-20 Andes Hantavirus Outbreak on a Cruise Ship, 2026 Spatial analysis in South Carolina revealed that measles infections were clustered in areas where public school vaccination rates were lower. https://www.nejm.org/doi/full/10.1056/NEJMc2604004?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2604004 Emily A. Serman, Brian Witrick, Lior Rennert 2026-05-20 Clusters of Concern — Spatial Link between Childhood Undervaccination and Measles Outbreaks in South Carolina Among patients with idiopathic pulmonary fibrosis, inhaled treprostinil led to a smaller decline in forced vital capacity than placebo over 52 weeks. Cough and drug discontinuation were more common with treprostinil. https://www.nejm.org/doi/full/10.1056/NEJMoa2501488?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2501488 Steven D. Nathan, Peter Smith, Chunqin Deng, Christopher S. King, Maria De Salvo, S. Samuel Weigt, Sahil Pandya, Debabrata Bandyopadhyay, Joseph A. Lasky, Rachana Krishna, Nathan Hambly, Murali Ramaswamy, Jad Kebbe, Neil Ettinger, Jamie Gao, Youlan Rao, Natalie Breytenbach, Leigh Peterson, Heidi Bell, Juergen Behr, Vincent Cottin, Kevin R. Flaherty, the TETON-1 Trial Investigators* 2026-05-18 Phase 3 Trials of Inhaled Treprostinil for Idiopathic Pulmonary Fibrosis Azithromycin did not lead to a greater reduction in symptom severity than placebo among preschool children presenting to the emergency department with wheezing, regardless of whether they tested positive for pathogenic bacteria. https://www.nejm.org/doi/full/10.1056/NEJMoa2516505?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2516505 Kurt R. Denninghoff, T. Charles Casper, Joseph J. Zorc, Richard M. Ruddy, Sarah Satola, Wendi-Jo Wendt, Claudia R. Morris, Melissa M. Tavarez, Matthew J. Lipshaw, Maria Y. Kwok, Jo-Ann O. Nesiama, Kyle A. Nelson, Michael Webb, Fernando D. Martinez, the PECARN AZ-SWED Trial Study Group* 2026-05-18 Azithromycin for Preschoolers with Wheezing in the Emergency Department Among patients with traumatic hemorrhage, prehospital transfusion of whole blood did not result in lower 30-day mortality than transfusion of plasma or red cells. Outcomes did not differ according to the storage age of blood. https://www.nejm.org/doi/full/10.1056/NEJMoa2602167?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2602167 Jason L. Sperry, Francis X. Guyette, Bryan A. Cotton, James F. Luther, Richard B. Utarnachitt, Matthew E. Kutcher, Brian J. Daley, Allan B. Peetz, Mayur B. Patel, Michael D. Goodman, Jeffrey A. Claridge, Nimitt Patel, Brian G. Harbrecht, Zain G. Hashmi, Ryan Zarychanski, Matthew D. Neal, Mark H. Yazer, Christian Martin-Gill, Laura E. Vincent, Ashley M. Harner, David E. Meyer, Andrew J. Latimer, Bryce R. Robinson, Catherine L. McKnight, William R. Hinckley, Keith R. Miller, Jan O. Jansen, Douglas Martin, Erin E. Fox, Bedda L. Rosario-Rivera, Stephen R. Wisniewski, the TOWAR Study Group* 2026-05-18 Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage An interim analysis of a phase 3 trial involving patients with IgA nephropathy showed that 39 weeks of treatment with telitacicept led to a greater reduction in the 24-hour urinary protein-to-creatinine ratio than placebo. https://www.nejm.org/doi/full/10.1056/NEJMoa2514415?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2514415 Jicheng Lv, Lijun Liu, Wenxiang Wang, Xinyue Wang, Qing Zuraw, Vlado Perkovic, Jianmin Fang, Hong Zhang, the TELIGAN Investigators* 2026-05-14 Telitacicept for IgA Nephropathy — Interim Analysis of a Phase 3 Trial In a trial, the 3C-like protease inhibitor ensitrelvir was more effective than placebo in preventing Covid-19 in household contacts of patients with SARS-CoV-2 infection. https://www.nejm.org/doi/full/10.1056/NEJMoa2509306?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2509306 Frederick G. Hayden, Masaharu Shinkai, Tristan W. Clark, Anne F. Luetkemeyer, Paul E. Sax, William P. Hanage, Kelly A. Gebo, Hideyuki Ikematsu, Koichi Izumikawa, Akimasa Fukushi, Safwan Kezbor, Hiroki Sakaguchi, Stuart Lacey, Genki Ichihashi, Norio Ohmagari, Takeki Uehara, the SCORPIO-PEP Study Team* 2026-05-14 Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts Among patients with stroke due to medium-vessel occlusion, thrombectomy led to functional independence at 90 days (in 58.6% of patients, vs. 46.6% with medical management) but also to a higher risk of intracranial hemorrhage. https://www.nejm.org/doi/full/10.1056/NEJMoa2514120?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2514120 Wei Hu, Xiaozhong Jing, Zhongjun Chen, Jin Zheng, Tingyu Yi, Tuanyuan Zheng, Zhide Li, Junzhong Liu, Tao Cui, Jianshang Wen, Ganghua Feng, Cunfeng Song, Lei Yang, Shunfu Jiang, Lin Tong, Changchun Jiang, Zhongfan Ruan, ˒Peiyang Zhou, Shouchun Wang, Tao Wang, Zhiming Zhou, Youquan Ren, Tao Qiu, Chong Zheng, Hao Wang, Yong Liu, Yun Luo, Jing Wang, Zhengfei Ma, Bin Mei, Yong Liang, Yuyou Zhu, Rui Li, Jun Sun, Li Wang, Chao Zhang, Tianlong Liu, Jianlong Song, Chunrong Tao, Anmo Wang, Jinjing Wang, Pengfei Xu, Xiaofan Guo, Liqi Shu, Adnan I. Qureshi, Thanh N. Nguyen, Mohamad AbdalKader, Jeffrey L. Saver, Wenhuo Chen, Raul G. Nogueira 2026-05-14 Endovascular Treatment of Medium-Vessel-Occlusion Strokes In a trial of brepocitinib in adults with dermatomyositis, the 30-mg dose (but not the 15-mg dose) led to greater improvement on a composite myositis index at 52 weeks than placebo. Serious infections were more frequent with the 30-mg dose. https://www.nejm.org/doi/full/10.1056/NEJMoa2503531?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2503531 Ruth Ann Vleugels, Julie J. Paik, Iazsmin Bauer Ventura, Aaron R. Mangold, Prateek C. Gandiga, Anna Haemel, Hector Chinoy, Yessar M. Hussain, Kumaraswamy Sivakumar, Zoltan Griger, Eun Bong Lee, Francisca Bozan, Chung-Yuan Hsu, Alisa Femia, Mazen M. Dimachkie, Michelle S. Min, Tahseen Mozaffar, Christina Charles-Schoeman, David R. Fernandez, Oluwakemi Onajin, Raquel Campanilho-Marques, Galina Marder, Floranne Ernste, Elena Schiopu, Jason Sluzevich, David Pearson, Stephen Lindsey, Michael Luggen, Michael R. Bubb, Erin Boh, Rashmi Maganti, Latisha Heinlen, Katharina S. Shaw, Matthew D. Cascino, Paul N. Mudd Jr., Jiri Vencovsky, Anthony P. Fernandez, David Fiorentino, Lisa Christopher-Stine, Victoria P. Werth, Rohit Aggarwal, the VALOR Investigators* 2026-05-14 A Phase 3 Trial of Brepocitinib in Dermatomyositis Inflammatory myopathies are typically associated with a myositis-specific autoantibody that determines the diagnosis and prognosis. Myositis subgroups have distinct pathomechanisms that now allow for targeted therapies. https://www.nejm.org/doi/full/10.1056/NEJMra2415426?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMra2415426 Yves Allenbach, Olivier Benveniste 2026-05-14 Inflammatory Myopathies A 50-year-old man presented to the ED with a 1-month history of headache and worsening weakness of the left arm and leg. Brain MRI showed an enhancing lesion with extensive surrounding edema. https://www.nejm.org/doi/full/10.1056/NEJMicm2518333?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2518333 Ke Xiao, Ying Si 2026-05-14 Cerebral Syphilitic Gumma There are times when something as apparently mundane as a patient’s small black suitcase full of medical supplies can remind a physician of both the ordinary and the extraordinary of their chosen field. https://www.nejm.org/doi/full/10.1056/NEJMp2513327?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2513327 Christie Rampersad 2026-05-14 Unpacking the Ordinary A 55-year-old man presented with cough, chest pain, and worsening dyspnea after being trapped in a burning house for 10 minutes. Bronchoscopy revealed carbonaceous deposits that extended along the airway (shown in a video). https://www.nejm.org/doi/full/10.1056/NEJMicm2517900?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2517900 Juan Huang, Cheng Yang 2026-05-14 Inhalation Injury from House Fire Smoke Dermatomyositis is a subgroup of idiopathic inflammatory myopathies — systemic autoimmune disorders that are typically characterized by the involvement of multiple organs, including muscle, skin, joints, lungs, gastrointestinal tract, and heart — all conditions with high morbidity and mortality.1 Treatment of myositis is based on off-label use of... https://www.nejm.org/doi/full/10.1056/NEJMe2604009?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2604009 Ingrid E. Lundberg 2026-05-14 A Phase 3 Trial of Brepocitinib in Dermatomyositis Clinicians are rightly expected to disclose their gaps in knowledge or their inability to forecast an outcome. Yet emerging AI tools often cannot, or will not, do the same. https://www.nejm.org/doi/full/10.1056/NEJMp2517624?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2517624 Andrea Sikora, Leo A. Celi, Raja-Elie E. Abdulnour 2026-05-14 Can AI Say “I Don’t Know”? A 65-year-old woman with cardiovascular risk factors presented with a 14-hour history of painless, worsening, blurry vision in the right eye (visual acuity, 20/400). Funduscopy showed diffuse retinal hemorrhages and venous dilatation. https://www.nejm.org/doi/full/10.1056/NEJMicm2518603?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2518603 Gil Calvão Santos 2026-05-14 Central Retinal-Vein Occlusion