The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Dermatology. NEJM (https://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. https://www.nejm.org/action/showPodcastsFeeds NEJM Group Mon, 08 Jun 2026 01:49:56 GMT 2026 NEJM Group en-us 1440 In a trial of brepocitinib in adults with dermatomyositis, the 30-mg dose (but not the 15-mg dose) led to greater improvement on a composite myositis index at 52 weeks than placebo. Serious infections were more frequent with the 30-mg dose. https://www.nejm.org/doi/full/10.1056/NEJMoa2503531?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2503531 Ruth Ann Vleugels, Julie J. Paik, Iazsmin Bauer Ventura, Aaron R. Mangold, Prateek C. Gandiga, Anna Haemel, Hector Chinoy, Yessar M. Hussain, Kumaraswamy Sivakumar, Zoltan Griger, Eun Bong Lee, Francisca Bozan, Chung-Yuan Hsu, Alisa Femia, Mazen M. Dimachkie, Michelle S. Min, Tahseen Mozaffar, Christina Charles-Schoeman, David R. Fernandez, Oluwakemi Onajin, Raquel Campanilho-Marques, Galina Marder, Floranne Ernste, Elena Schiopu, Jason Sluzevich, David Pearson, Stephen Lindsey, Michael Luggen, Michael R. Bubb, Erin Boh, Rashmi Maganti, Latisha Heinlen, Katharina S. Shaw, Matthew D. Cascino, Paul N. Mudd Jr., Jiri Vencovsky, Anthony P. Fernandez, David Fiorentino, Lisa Christopher-Stine, Victoria P. Werth, Rohit Aggarwal, the VALOR Investigators* 2026-05-14 A Phase 3 Trial of Brepocitinib in Dermatomyositis Dermatomyositis is a subgroup of idiopathic inflammatory myopathies — systemic autoimmune disorders that are typically characterized by the involvement of multiple organs, including muscle, skin, joints, lungs, gastrointestinal tract, and heart — all conditions with high morbidity and mortality.1 Treatment of myositis is based on off-label use of... https://www.nejm.org/doi/full/10.1056/NEJMe2604009?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2604009 Ingrid E. Lundberg 2026-05-14 A Phase 3 Trial of Brepocitinib in Dermatomyositis In this randomized trial, higher-dose ivermectin plus permethrin was no better than standard-dose ivermectin plus permethrin, but both regimens were effective, leading to cure in 75% and 82% of the patients, respectively. https://www.nejm.org/doi/full/10.1056/NEJMoa2411721?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2411721 Charlotte Bernigaud, Giao Do-Pham, Elie Guichard, Marie Beylot-Barry, Elisa Goujon, Camille Isnard, Nathalie Beneton, Mahtab Samimi, Billal Tedbirt, Henri Adamski, Selma Azib, Emmanuel Mahé, Catherine Michel, Jean-Luc Perrot, Marie Acquitter, Anne-Claire Bursztejn, Guillaume Chaby, Frédéric Caux, Thierry Passeron, Clélia Vanhaecke, Antoine Mahé, Marie-Thérèse Leccia, Sébastien Barbarot, Cédric Lenormand, François Aubin, Françoise Foulet, Laëtitia Grégoire, Bruno Giraudeau, Olivier Chosidow 2026-05-07 Combined Oral Ivermectin and 5% Permethrin Cream to Treat Severe Scabies A 22-year-old man presented with a 5-day history of painful lesions on his hands, feet, lips, and tongue. Physical examination showed erosions on the tongue and target lesions on the palms. https://www.nejm.org/doi/full/10.1056/NEJMicm2517901?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2517901 Inês Pereira Amaral, Joana Antunes 2026-05-07 Erythema Multiforme A 30-year-old man who worked as an agricultural laborer presented with a 2-year history of skin lesions on his right foot. Examination was notable for swelling of the right foot with overlying ulcerated nodules. https://www.nejm.org/doi/full/10.1056/NEJMicm2515474?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2515474 Juan C. Cataño, Valentina Montoya 2026-04-30 Mycetoma A 76-year-old woman, who had a history of treated hepatitis C virus infection, presented with rapidly progressive kidney failure and a stroke. Palpable purpura on the legs was noted. A diagnosis was made. https://www.nejm.org/doi/full/10.1056/NEJMcpc2517862?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcpc2517862 Frank B. Cortazar, Meghan E. Sise, Otto Rapalino, Andrew R. Branagan, Claire Trivin-Avillach 2026-04-30 Case 13-2026: A 76-Year-Old Woman with Fatigue, Rash, and Kidney Failure A 27-year-old woman presented with a 2-week history of joint pain, fever, sore throat, and a nonpruritic rash that worsened during fever. Laboratory tests showed an elevated ESR and elevated C-reactive protein and ferritin levels. https://www.nejm.org/doi/full/10.1056/NEJMicm2514594?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2514594 Gabrielle Cognacq, Richard Stratton 2026-04-16 Adult-Onset Still’s Disease Among patients with moderate or severe PTS, the addition of endovascular therapy to standard care resulted in less severe PTS and better quality of life at 6 months than standard care alone but with a higher risk of bleeding. https://www.nejm.org/doi/full/10.1056/NEJMoa2519001?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2519001 Suresh Vedantham, Susan R. Kahn, William A. Marston, Ido Weinberg, Akhilesh K. Sista, Elizabeth A. Magnuson, David J. Cohen, Suman M. Wasan, Mahmood K. Razavi, Samuel Z. Goldhaber, Kristen M. Sanfilippo, Anthony J. Comerota, Ezana M. Azene, Cassius Iyad Ochoa Chaar, Daniel A. Leung, K. Pallav Kolli, Sanjeeva P. Kalva, Nassir Rostambeigi, Ajinkya Desai, Kush R. Desai, Alfonso J. Tafur, Bhavraj Khalsa, Elaine Majerus, Borong Wang, Yang Wang, Patricia Nieters, Mary Clare Derfler, Angela Oliver, Cassandra Hardy, Riyaz Bashir, Ronald Winokur, Natalie Weger, Minhaj S. Khaja, Aditya Sharma, Naganathan Mani, Pavan Kavali, Siddhant Thukral, Leslie L. Lake, Kathryn Mikkelsen, Sameer Parpia, the C-TRACT Trial Investigators* 2026-04-13 Endovascular Therapy for Post-Thrombotic Syndrome — A Randomized Trial Post-thrombotic syndrome is the most common chronic complication of deep-vein thrombosis (DVT), affecting 20 to 50% of patients with DVT and causing debilitating symptoms involving the limbs — including pain, swelling, skin changes, and venous ulcers — that substantially reduce quality of life and impose considerable socioeconomic burden.1 ... https://www.nejm.org/doi/full/10.1056/NEJMe2603048?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2603048 Ronald Luiz Gomes Flumignan, Luís Carlos Uta Nakano 2026-04-13 Stenting for Post-Thrombotic Syndrome — A Step Forward This review summarizes the epidemiology, diagnosis, and management of celiac disease and highlights serologic testing, biopsy confirmation, associated autoimmune conditions, and a gluten-free diet as treatment. https://www.nejm.org/doi/full/10.1056/NEJMcp2415548?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcp2415548 Joseph A. Murray, Steffen Husby 2026-04-09 Celiac Disease An 83-year-old woman with worsening type 2 diabetes presented with a 6-month history of painful rash. Hyperpigmented plaques with coalescing erosions and blisters were seen. Abdominal CT revealed a mass in the tail of the pancreas. https://www.nejm.org/doi/full/10.1056/NEJMicm2516331?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2516331 Jia-An Hung, Ming-Chieh Lin 2026-04-09 Necrolytic Migratory Erythema A 68-year-old woman with rosacea presented with a 6-week history of dark patches on the skin of her arms and legs. Two weeks before the onset of the skin changes, she had started taking minocycline daily. https://www.nejm.org/doi/full/10.1056/NEJMicm2513782?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2513782 Aarti Maharaj, Michael Omar 2026-04-02 Minocycline-Induced Hyperpigmentation A 33-year-old pregnant woman with previously controlled atopic dermatitis presented with 3 days of fever and an itchy, painful rash. Erythematous vesiculopapular lesions were noted on the face, neck, chest, and arms. https://www.nejm.org/doi/full/10.1056/NEJMicm2516038?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2516038 Heba H.A.H.Y. AlBaloul, Carson K.L. Lo 2026-03-26 Eczema Herpeticum A 49-year-old woman presented with a 6-month history of an itchy lump on her vulva. Examination showed a painless purple mass originating in the labia minora on the left side. https://www.nejm.org/doi/full/10.1056/NEJMicm2509511?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2509511 Francisco Javier Castro-Apodaca, Adrian Canizalez-Roman 2026-03-12 Vulvar Melanoma with Vaginal Extension A woman presented with a 1-year history of a crawling sensation on her chin that caused her to scratch the area. An irregular ulcer was present on the right side of her chin, with reduced sensation around the mouth, lip, and chin. https://www.nejm.org/doi/full/10.1056/NEJMicm2512031?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2512031 Anna Kersh, Janine Lobo Lopes 2026-03-05 Trigeminal Trophic Syndrome Medicare will achieve greater savings on the 15 drugs in its second round of price negotiations than it did in the first round. Despite new challenges, the effort should continue to pay growing dividends. https://www.nejm.org/doi/full/10.1056/NEJMp2517584?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2517584 Benjamin N. Rome, Aaron S. Kesselheim 2026-02-26 The Growing Success of Medicare Drug-Price Negotiation A previously healthy man presented with a 5-day history of fever, nausea, and vomiting and a 2-day history of an itchy rash. Examination showed an exanthem consisting of minute macules and subtly elevated papules. https://www.nejm.org/doi/full/10.1056/NEJMicm2514397?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2514397 Maximilian Lammer, Barbara C. Böckle 2026-02-26 Primary Measles Infection A high-school wrestler presented with an itchy rash that had worsened despite topical antifungal and glucocorticoid treatment. A circular, scaly plaque with papules, nodules, and pustules was seen on his calf. https://www.nejm.org/doi/full/10.1056/NEJMicm2509457?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2509457 Ciara A. Maguire, Seth J. Orlow 2026-02-19 Majocchi’s Granuloma A 55-year-old woman with invasive ductal carcinoma presented with a rash that had developed after a round of chemotherapy and had worsened and spread to her axillae, groin, and popliteal fossae after several additional rounds. https://www.nejm.org/doi/full/10.1056/NEJMicm2513411?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2513411 Shihua Ling, Xia Dou 2026-01-29 Toxic Erythema of Chemotherapy In resected stage III or IV melanoma, nivolumab improved 9-year recurrence-free survival as compared with ipilimumab (44% vs. 37%), with no new late adverse events and fewer subsequent therapies needed. https://www.nejm.org/doi/full/10.1056/NEJMoa2504966?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2504966 Paolo A. Ascierto, Michele Del Vecchio, Barbara Merelli, Helen Gogas, Ana M. Arance, Stéphane Dalle, Charles Lance Cowey, Michael Schenker, Caroline Gaudy-Marqueste, Jacopo Pigozzo, Iván Márquez-Rodas, Marcus O. Butler, Anna Maria Di Giacomo, Oleg Gligich, Luis De La Cruz-Merino, Petr Arenberger, Victoria Atkinson, Paul Nathan, Andrew Hill, Michael Millward, Leslie A. Fecher, Nikhil I. Khushalani, Paola Queirolo, Raheela Soomro, Dhanrajsinh Rathod, Margarita Askelson, Melanie Pe Benito, Devanand Joseph, James Larkin 2026-01-22 Nivolumab for Resected Stage III or IV Melanoma at 9 Years