The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Infectious Disease. NEJM (https://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. https://www.nejm.org/action/showPodcastsFeeds NEJM Group Sun, 19 Apr 2026 23:55:27 GMT 2026 NEJM Group en-us 1440 Consolidation in drug markets could promote availability of innovative treatments. But current antitrust screening is inadequate for detecting anticompetitive behavior, including “killer acquisitions.” https://www.nejm.org/doi/full/10.1056/NEJMp2516842?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2516842 S. Sean Tu, Jaime King 2026-04-18 Anticompetitive Mergers — Pharmaceutical Buyouts as a Strategy for Maintaining Market Dominance In this trial involving patients undergoing mechanical ventilation in the ICU, selective decontamination of the digestive tract did not result in a lower incidence of in-hospital death than standard care alone. https://www.nejm.org/doi/full/10.1056/NEJMoa2506398?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2506398 The SuDDICU Investigators for the Australia and New Zealand Intensive Care Society Clinical Trials Group and the Canadian Critical Care Trials Group 2026-04-16 Selective Decontamination of the Digestive Tract during Ventilation in the ICU In critical care, selective digestive decontamination (SDD) is the elephant in the room. Cluster-randomized trials, individually randomized trials, and meta-analyses have shown that the use of SDD is associated with a decreased risk of ventilator-associated pneumonia, of hospital-onset bacteremia, and in some studies, of death.1,2 Nonetheless, very few... https://www.nejm.org/doi/full/10.1056/NEJMe2602823?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2602823 Michael Klompas 2026-04-16 Selective Digestive Decontamination — Finding the Way Forward This Double Take video reviews the differential diagnosis for a woman with night sweats and unintentional weight loss and how it evolves as new clinical findings are presented. https://www.nejm.org/doi/full/10.1056/NEJMp2516852?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2516852 Sarah Gorey, Alison E. Burke, Natalie Koscal, Emily Ling, Nadine Tan, Caren G. Solomon 2026-04-16 Double Take: The Devil Is in the Details In the final NOS episode of the season, host Lisa Rosenbaum and her guests elucidate the quiet beauty of good primary care and consider how to induce the U.S. health care system to prize it more highly. https://www.nejm.org/doi/full/10.1056/NEJMp2514244?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2514244 2026-04-16 Not Otherwise Specified — Season 3: The Forever Crisis of Primary Care: When No One’s Watching — NOS Episode 3.12 The Trump administration’s wide-ranging actions to dismantle U.S. environmental regulations will cause long-lasting health harms, disproportionately affecting low-income and other vulnerable groups. https://www.nejm.org/doi/full/10.1056/NEJMp2514370?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2514370 Adam W. Gaffney, David Himmelstein, Steffie Woolhandler, Sancia Sehdev, Philip J. Landrigan 2026-04-16 The Dismantling of Environmental Protections — A Grave Threat to America’s Health A 16-year-old girl presented with 1 month of ankle pain and 11 days of fever. Radiographs showed an ill-defined, radiolucent distal tibial lesion; on MRI, the lesion was hypointense and surrounded by a hyperintense sclerotic rim. https://www.nejm.org/doi/full/10.1056/NEJMicm2514540?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2514540 Haijian Li, Pei Han 2026-04-16 Intraosseous Abscess from Subacute Osteomyelitis Despite the erosion of public confidence in science and medicine, nurses remain highly trusted professionals. Integrating nurse scientists into health communication strategies would benefit public health. https://www.nejm.org/doi/full/10.1056/NEJMp2518286?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2518286 Paule Joseph, Mayu O. Frank, Rita Devine, Jill McCabe, Bernadette Capili 2026-04-16 Nurse Scientists as Trusted Voices in Health Communication In a Brazilian self-controlled case series of 5055 hospitalizations for Guillain–Barré syndrome, laboratory-confirmed dengue was associated with an increased risk of Guillain–Barré syndrome occurring within 42 days. https://www.nejm.org/doi/full/10.1056/NEJMc2519008?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2519008 Thiago Cerqueira-Silva, Enny Paixão, Giovanny V.A. França, Luiza X.S. Tenório, Mateus C. Amaral, Nubia M. Santos, Neil Pearce, Viviane S. Boaventura, Manoel Barral-Netto 2026-04-16 Risk of Guillain–Barré Syndrome after Laboratory-Confirmed Dengue Infection In this trial, a new yellow fever vaccine grown in Vero cells was shown to elicit immunogenicity similar to that of the standard yellow fever vaccine. https://www.nejm.org/doi/full/10.1056/NEJMoa2505665?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2505665 Emmanuel Feroldi, Mark J. Mulligan, Kawsar R. Talaat, Chen Sabrina Tan, Kristopher Paolino, Srilatha Edupuganti, Matthew H. Collins, Sarah L. George, Matthew Davis, Brandon Essink, Robert Jeanfreau, James Peterson, David Fried, Ada-Maria Minutello, Sandrine Orlando, Joanna Korejwo, Andrey Rojas, Marine Dufournet, Tifany Machabert, Louis Devlin, Carina Frago, the vYF Vaccine Study Team* 2026-04-09 Immunogenicity and Safety of vYF, a Yellow Fever Vaccine — A Phase 2 Trial A 68-year-old woman with rosacea presented with a 6-week history of dark patches on the skin of her arms and legs. Two weeks before the onset of the skin changes, she had started taking minocycline daily. https://www.nejm.org/doi/full/10.1056/NEJMicm2513782?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2513782 Aarti Maharaj, Michael Omar 2026-04-02 Minocycline-Induced Hyperpigmentation A Tennessee bill focused on directed blood donation exemplifies a pattern of efforts to legislate medical practice in ways that override scientific consensus while invoking the language of autonomy. https://www.nejm.org/doi/full/10.1056/NEJMp2602587?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2602587 Jeremy W. Jacobs, Nikki B. Zite, Miriam Brown, Sarah S. Osmundson, Deva Sharma 2026-04-01 Legislating Medicine — Directed Donation and the Politics of Patient Choice In this report from Singapore, the release of wolbachia-infected, irradiated male Aedes aegypti mosquitoes resulted in a reduction in the vector population and in the risk of dengue infection. https://www.nejm.org/doi/full/10.1056/NEJMoa2503304?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2503304 Jue Tao Lim, Chee-Seng Chong, Chia-Chen Chang, Diyar Mailepessov, Borame Dickens, Yee Ling Lai, Lu Deng, Caleb Lee, Li Yun Tan, Grace Chain, Muhammad Faizal Zulkifli, Jonathan Wee Kent Liew, Kathryn Vasquez, Man Ling Chau, Youming Ng, Vernon Lee, Judith Chui Ching Wong, Shuzhen Sim, Cheong Huat Tan, Lee Ching Ng, the Project Wolbachia–Singapore Consortium* 2026-03-26 Dengue Suppression by Male Wolbachia-Infected Mosquitoes In this study, gene editing with a prime editor was used to treat two persons with chronic granulomatous disease caused by a small deletion in the gene NCF1. https://www.nejm.org/doi/full/10.1056/NEJMoa2509807?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2509807 Jennifer L. Gori, Elie Haddad, Haydar Frangoul, Donald B. Kohn, Emma C. Morris, Bradley N. Martin, Briana A. Deary, McKinley Nickerson, Rebecca L. Scholz, Isabel Fernandez, Karine Leveille, Suk See De Ravin, Elizabeth M. Kang, Marie Pierzynski, Tyra Estwick, Patricia Littel, Douglas B. Kuhns, Debra A. Long Priel, Pierre Teira, Stuart Turvey, Jordyn Arnold, Misty D. Evans, Meghann McManus, Ben Carpenter, David P. Waterman, Andrew V. Anzalone, Alexandria Petrusich, Christa E. Osuna, Tiernan T. O’Malley, Jacob Stewart-Ornstein, Jack M. Heath, Barrett J. Nehilla, Mohammed Asmal, Harry L. Malech 2026-03-26 Brief Report: Prime Editing for p47phox-Deficient Chronic Granulomatous Disease Immunodeficiency chronic granulomatous disease (CGD) is a rare disorder characterized by defects in a multiprotein complex that generates superoxide in phagocytic cells.1 Recurrent infections and formation of granulomas are hallmarks of X-linked and autosomal-recessive CGD, which is caused by variants in genes encoding individual subunits. As a monogenic... https://www.nejm.org/doi/full/10.1056/NEJMe2601003?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2601003 Daniel E. Bauer, Stuart H. Orkin 2026-03-26 Genetic Medicine — Primed and Ready A 33-year-old pregnant woman with previously controlled atopic dermatitis presented with 3 days of fever and an itchy, painful rash. Erythematous vesiculopapular lesions were noted on the face, neck, chest, and arms. https://www.nejm.org/doi/full/10.1056/NEJMicm2516038?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2516038 Heba H.A.H.Y. AlBaloul, Carson K.L. Lo 2026-03-26 Eczema Herpeticum Recent changes in U.S. vaccine policy are sowing confusion and threatening the health of children and the wider population. How should pediatric clinicians communicate with parents to stem the damage? https://www.nejm.org/doi/full/10.1056/NEJMp2600539?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2600539 Douglas J. Opel, Sean T. O’Leary 2026-03-26 Communicating about Vaccines in a Politically Contentious Climate Infection with Japanese encephalitis virus, a mosquito-borne flavivirus, was identified in a patient who received a liver transplant from a donor who resided in California. https://www.nejm.org/doi/full/10.1056/NEJMc2514269?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2514269 Hannah Padda, Susan Hills, Charles Y. Chiu, Venice Servellita, Allan M. Seibert, Holly R. Hughes, Jennifer Lehman, Kelly Fitzpatrick, Amy Lambert, Jessica Spring, Kristen L. Burkhalter, Roxanne Connelly, Aaron Brault, Randall J. Nett, Natalia P. Arizmendez, Sarah J. Beesley, Nick M. Murray, Michael Lanspa, Jean F. Botha, Sumit J. Patel, Helen Bixenman, Mark Edmunds, Walter Kelley, Andrea J. Lund, Mary Danforth, Mary Kate Morris, Hannah Romo, Van Ngo, Umme-Aiman Halai, Erik A. Berg, Christine Hahn, Kacy Nowak, Christopher M. Barker, Audrey Kennar, Kelsey McDavid, Pallavi Annambhotla, Ian Kracalik, Sridhar V. Basavaraju, J. Erin Staples, Carolyn V. Gould 2026-03-26 Probable Japanese Encephalitis Virus Transmission through Organ Transplantation Tuberculosis remains a leading cause of death worldwide among persons with HIV. In this report, the effect of the PEPFAR program on incident cases of tuberculosis and related deaths is presented. https://www.nejm.org/doi/full/10.1056/NEJMc2506284?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2506284 Jonathan P. Smith, Stephanie O’Connor, Anand Date, Patrick K. Moonan 2026-03-24 Tuberculosis Cases and Deaths Averted by PEPFAR A 73-year-old woman presented in shock with a 1-day history of malaise, dyspnea, and confusion. Serum samples could not be processed owing to gross hemolysis. Dehemoglobinized red cells and bacilli were seen on a peripheral-blood smear. https://www.nejm.org/doi/full/10.1056/NEJMicm2514135?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2514135 Ann Tran, Carol Lee 2026-03-12 Massive Intravascular Hemolysis from Clostridium perfringens Bacteremia