The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Infectious Disease. NEJM (https://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. https://www.nejm.org/action/showPodcastsFeeds NEJM Group Thu, 04 Jun 2026 06:05:23 GMT 2026 NEJM Group en-us 1440 Vaccine hesitancy is often driven by safety concerns. Clinician recommendations, presumptive communication, and empathy improve uptake; maintaining trust supports future acceptance and community protection. https://www.nejm.org/doi/full/10.1056/NEJMcp2516616?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcp2516616 Sean T. O’Leary, Margie Danchin 2026-06-04 Childhood Vaccine Hesitancy A 53-year-old man with Crohn’s disease and psoriasis presented with a 2-day history of headache, slurred speech, nausea, and vomiting. During the previous 2 weeks, he had had yellowing of the skin and eyes and dark urine. https://www.nejm.org/doi/full/10.1056/NEJMcps2506943?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcps2506943 Brittany B. Bromfield, Nikroo Hashemi, Mark S. Redston, Katherine H. Walker, Bruce D. Levy 2026-06-04 The Unusual Suspects The prevalence of wasting among children in Gaza tracks with Israeli blockades on aid, but war may lead to famine even without such policies. How should starvation be prevented and treated in wartime? https://www.nejm.org/doi/full/10.1056/NEJMp2602465?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2602465 Kevin Stephenson, Christa Lolley, Mark Manary 2026-06-04 War and Famine In an African study of severe malaria in children with partially artemisinin-resistant parasites with PfK13 mutations, artesunate did not lead to worse outcomes, which suggests that parenteral artesunate may still be used. https://www.nejm.org/doi/full/10.1056/NEJMc2517274?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2517274 Kathryn Maitland, Maurice Okao, Melissa D. Conrad, Tonny Etwop, Modester Akite, Emmanuel Oguda, Florence Alaroker, Denis Aromut, Rita Muhindo, Sophie Uyoga, Peter Olupot-Olupot, Christabel Mogaka, Roisin Connon, Thomas Katairo, Martin Okitwi, Jessica Briggs, Diana M. Gibb, Nicholas P.J. Day, Nicholas J. White, Thomas N. Williams, Arjen M. Dondorp, A. Sarah Walker, Elizabeth C. George, Philip J. Rosenthal, for the SMAART-CHARISMA group† 2026-06-03 Intravenous Artesunate in Artemisinin-Resistant Severe Malaria in Uganda In January 2025, an outbreak of disease caused by Sudan virus, an ebolavirus, was identified in Uganda. Characteristics of this outbreak are described. https://www.nejm.org/doi/full/10.1056/NEJMc2508159?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2508159 Henry Kyobe Bosa, Misaki Wayengera, Winters Muttamba, Andrew Nsawotebba, Daniel Kiiza, Allan Muruta, Suzan Nabadda, Rony Bahatungire, Annet Alenyo Ngabirano, Stavia Turyahabwe, Bernard Lubwama, Patrick Okumu Abok, Miriam Nanyunja, Andrew Bakainaga, Daniel Kadobera, Francis Bakehena, Daniel Bulwadda, Bruce Kirenga, Barnabas Bakamutumaho, Kasonde Mwinga, Charles Olaro, Diana Atwine, Jane Ruth Aceng, for the SVD Response Team* 2026-06-03 Sudan Virus Disease in Uganda, 2025 In two phase 3 trials, 19% of patients with chronic hepatitis B infection had a functional cure with the antisense oligonucleotide bepirovirsen, 24 weeks after stopping all HBV treatment; functional cure was not seen with placebo. https://www.nejm.org/doi/full/10.1056/NEJMoa2515131?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2515131 Jinlin Hou, Seng-Gee Lim, Maria Buti, Man-Fung Yuen, Edward Gane, Pietro Lampertico, Norah Terrault, Huy Nguyen, Hyung Joon Yim, Qing Xie, Jianmei Lin, Yunqing Qiu, Wen-Juei Jeng, Jeong Heo, Cheng-Yuan Peng, Chien-Hung Chen, Wan-Long Chuang, Yao Xie, Maria Hlebowicz, Nevin Idriz, Rajiv Mehta, Kosh Agarwal, Monica M. Gomes da Silva, Alex Franca, Roxana Cernat, Apinya Leerapun, Carla S. Coffin, Adrian Gadano, Pietro Andreone, Shigetoshi Fujiyama, Vasileios Sevastianos, Yuichiro Suzuki, Vlad Ratziu, Ghassan Riachi, Hartmut Stocker, Tien Huey Lim, Tarik Asselah, Yasuhito Tanaka, Jacinta Holmes, Xieer Liang, Jennifer Cremer, Tamara Lukić, Helene Plein, Geoff Quinn, Yu Tao, Melanie Paff, Dickens Theodore, Robert Elston, the B-Well Study Group* 2026-05-28 Phase 3 Results of Bepirovirsen Treatment for Chronic Hepatitis B Virus Infection Leishmaniases are clinically distinct parasitic diseases transmitted by infected sand flies. Laboratory diagnosis has shifted to molecular methods. Treatment choices are limited; two vaccines are being tested. https://www.nejm.org/doi/full/10.1056/NEJMra2403309?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMra2403309 Naomi E. Aronson, Ahmed M. Musa, Abhay R. Satoskar 2026-05-28 Leishmaniasis Research on Lyme disease has emphasized clinical disease and pathogen microbiology rather than the root cause: the infected tick vectors in the environment, which remain uncontrolled. https://www.nejm.org/doi/full/10.1056/NEJMp2516974?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2516974 Durland Fish 2026-05-28 Getting Serious about Tickborne Diseases — Shifting Research Priorities The current treatment of chronic hepatitis B infection includes nucleoside or nucleotide analogue (NA) therapy and pegylated interferon. Both of these treatments are effective in suppressing hepatitis B virus (HBV) replication and in reducing the risk of cirrhosis and hepatocellular carcinoma.1 However, these treatments do not eradicate HBV,... https://www.nejm.org/doi/full/10.1056/NEJMe2605575?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2605575 Anna S. Lok 2026-05-28 A Major Step toward a Cure for Hepatitis B Infection A 64-year-old woman presented with fatigue, memory changes, and falls. MRI of the head revealed numerous hyperintense foci in the white matter on fluid-attenuated inversion recovery images. A diagnosis was made. https://www.nejm.org/doi/full/10.1056/NEJMcpc2517865?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcpc2517865 Shamik Bhattacharyya, Samuel C.D. Cartmell, Albert Y. Hung, Philippe A. Bilodeau, Elizabeth C. Conner 2026-05-28 Case 15-2026: A 64-Year-Old Woman with Fatigue, Memory Changes, and Falls Two patients with inborn errors of immunity and progressive multifocal leukoencephalopathy received polyomavirus-specific T cells, followed by allogeneic hematopoietic transplantation with good neurologic outcomes. https://www.nejm.org/doi/full/10.1056/NEJMc2514186?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2514186 Corina E. Gonzalez, Anita Fletcher, Tonya L. Jenkins, Sara Zahraeifard, Rose Peterson, Milo Taylor, Christine Jones, Amanda Urban, Daniele Avila, Mauricio Campillay, Jamie Wilhelm, Ariane Soldatos, Jens Kuhle, Poorva Jain, Sydney Corey, Jenna R.E. Bergerson, Daniel S. Reich, Steven Highfill, David Stroncek, Anh Dinh, Stefania Pittaluga, Heidi H. Kong, Helen C. Su, Luigi D. Notarangelo, Sung-Yun Pai, Michael Grimley, Alexandra F. Freeman, Irene Cortese 2026-05-28 Resolution of PML after Treatment with Virus-Specific T Cells and HCT On May 2, hantavirus infection was diagnosed in a patient who had been on a cruise ship. Subsequent evaluation revealed multiple cases of Andes hantavirus infection on the ship. To date, three associated deaths have occurred. https://www.nejm.org/doi/full/10.1056/NEJMc2606496?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2606496 Andes Virus Outbreak Working Group 2026-05-20 Andes Hantavirus Outbreak on a Cruise Ship, 2026 Spatial analysis in South Carolina revealed that measles infections were clustered in areas where public school vaccination rates were lower. https://www.nejm.org/doi/full/10.1056/NEJMc2604004?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2604004 Emily A. Serman, Brian Witrick, Lior Rennert 2026-05-20 Clusters of Concern — Spatial Link between Childhood Undervaccination and Measles Outbreaks in South Carolina In a trial, the 3C-like protease inhibitor ensitrelvir was more effective than placebo in preventing Covid-19 in household contacts of patients with SARS-CoV-2 infection. https://www.nejm.org/doi/full/10.1056/NEJMoa2509306?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2509306 Frederick G. Hayden, Masaharu Shinkai, Tristan W. Clark, Anne F. Luetkemeyer, Paul E. Sax, William P. Hanage, Kelly A. Gebo, Hideyuki Ikematsu, Koichi Izumikawa, Akimasa Fukushi, Safwan Kezbor, Hiroki Sakaguchi, Stuart Lacey, Genki Ichihashi, Norio Ohmagari, Takeki Uehara, the SCORPIO-PEP Study Team* 2026-05-14 Ensitrelvir for Covid-19 Postexposure Prophylaxis in Household Contacts A 50-year-old man presented to the ED with a 1-month history of headache and worsening weakness of the left arm and leg. Brain MRI showed an enhancing lesion with extensive surrounding edema. https://www.nejm.org/doi/full/10.1056/NEJMicm2518333?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2518333 Ke Xiao, Ying Si 2026-05-14 Cerebral Syphilitic Gumma Among adults 50 years of age or older, fewer cases of confirmed influenza-like illness were observed with an mRNA influenza vaccine than with standard vaccines. Reactogenicity was higher with the mRNA vaccine. https://www.nejm.org/doi/full/10.1056/NEJMoa2516491?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2516491 Isabel Leroux-Roels, Grace Huang, Murdo Ferguson, Anita Kohli, Rebecca Clark, Markus Bickel, Mieke Soens, Evelyn Du, Alicia Pucci, Bryony Hicks, Colbie Eschen, Rituparna Das, Eleanor Wilson, the Fluent Trial Investigators* 2026-05-07 Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults In this randomized trial, higher-dose ivermectin plus permethrin was no better than standard-dose ivermectin plus permethrin, but both regimens were effective, leading to cure in 75% and 82% of the patients, respectively. https://www.nejm.org/doi/full/10.1056/NEJMoa2411721?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2411721 Charlotte Bernigaud, Giao Do-Pham, Elie Guichard, Marie Beylot-Barry, Elisa Goujon, Camille Isnard, Nathalie Beneton, Mahtab Samimi, Billal Tedbirt, Henri Adamski, Selma Azib, Emmanuel Mahé, Catherine Michel, Jean-Luc Perrot, Marie Acquitter, Anne-Claire Bursztejn, Guillaume Chaby, Frédéric Caux, Thierry Passeron, Clélia Vanhaecke, Antoine Mahé, Marie-Thérèse Leccia, Sébastien Barbarot, Cédric Lenormand, François Aubin, Françoise Foulet, Laëtitia Grégoire, Bruno Giraudeau, Olivier Chosidow 2026-05-07 Combined Oral Ivermectin and 5% Permethrin Cream to Treat Severe Scabies A 22-year-old man presented with a 5-day history of painful lesions on his hands, feet, lips, and tongue. Physical examination showed erosions on the tongue and target lesions on the palms. https://www.nejm.org/doi/full/10.1056/NEJMicm2517901?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2517901 Inês Pereira Amaral, Joana Antunes 2026-05-07 Erythema Multiforme A 62-year-old man was admitted to the hospital for malaise, anorexia, rash, and diffuse lymphadenopathy. Fatigue and anorexia began 6 months earlier. Four months before admission, a pruritic rash developed on the back and spread. https://www.nejm.org/doi/full/10.1056/NEJMcps2511351?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcps2511351 Masami Matsumura, Naoki Kanda, Shuji Hatakeyama, Gurpreet Dhaliwal 2026-05-07 Immune Interference In a study involving 180 blood bags, use of a double-knot closure rather than the usual single knot prevented bacterial contamination. This strategy may reduce the risk of blood-product contamination in resource-limited settings. https://www.nejm.org/doi/full/10.1056/NEJMc2600589?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2600589 Kathleen Selleng, Halima Ismail, Christian Kohler, Jan Wesche, Jessica Fuhrmann, Anne Kohler, Claudia Wiede, Vivien Huj, Yazid Ibrahim, Evgeny A. Idelevich, Dalhat Gwarzo, Andreas Greinacher 2026-05-07 Reducing Bacterial Contamination of Blood Bags with a Double Knot