The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Surgery. NEJM (https://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. https://www.nejm.org/action/showPodcastsFeeds NEJM Group Mon, 27 Jul 2026 22:00:43 GMT 2026 NEJM Group en-us 1440 A man presented with a 2-month history of chest heaviness and a 2-week history of shortness of breath. Pulsations were visible between his ribs (shown in a video). Ultrasonography revealed a rounded structure near the heart. https://www.nejm.org/doi/full/10.1056/NEJMicm2505469?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2505469 Maithili Charan Gattu, Mehul K 2026-07-16 Descending Thoracic Aortic Aneurysm After total hip or knee arthroplasty, aspirin alone was noninferior to rivaroxaban followed by aspirin in preventing symptomatic venous thromboembolism, with a similarly low risk of bleeding complications. https://www.nejm.org/doi/full/10.1056/NEJMoa2603649?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2603649 Sudeep Shivakumar, Davide Matino, David Zukor, Susan R. Kahn, George Vincent, Raman Mundi, Pascal-Andre Vendittoli, Mohammad Refaei, Eric Bohm, Michael Tanzer, Stéphane Pelet, Glen Richardson, James Powell, Rick Ikesaka, James Douketis, Sarah Ward, Paul Kim, Stephen Mann, Susan Pleasance, Jocelyn Cormier, Pantelis Andreou, Kara Matheson, Chris Theriault, Carol West, David Anderson, Peter L. Gross, the EPCAT III Trial Investigators* 2026-07-12 Rivaroxaban Then Aspirin vs. Aspirin Alone after Total Hip or Knee Arthroplasty A 68-year-old man was evaluated in an outpatient clinic because of fatigue and dyspnea. Lung transplantation had been performed 15 months earlier. A diagnosis was made. https://www.nejm.org/doi/full/10.1056/NEJMcpc2517856?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcpc2517856 Hilary J. Goldberg, Harikrishnan Nandakumar, Brian C. Keller, Lida P. Hariri, Arthur Y. Kim, Briana N. Castillo 2026-07-09 Case 19-2026: A 68-Year-Old Man with Fatigue, Fever, and Hypoxemia Growing acceptance of voluntary euthanasia, which opens the door to death by organ donation, warrants a recontextualization of the dead donor rule and assessment of the ethical principles involved. https://www.nejm.org/doi/full/10.1056/NEJMms2601611?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMms2601611 Carter Winberg, Ian Ball, Robert D. Truog 2026-07-09 Contextualizing the Dead Donor Rule in an Era of Voluntary Euthanasia A 71-year-old man was found to have a tapeworm (shown in a video) in his peritoneal cavity during elective repair of a right inguinal hernia. He recalled having consumed raw snake meat during his military service 50 years earlier. https://www.nejm.org/doi/full/10.1056/NEJMicm2603440?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2603440 Chang-Seop Lee, Yeon Jun Jeong 2026-07-09 Sparganosis A 56-year-old woman was hospitalized with gait instability. Eight weeks earlier, she had noticed ascending symmetric sensations of painful “pins and needles” that had begun in her feet; she later had memory impairment and irritability. https://www.nejm.org/doi/full/10.1056/NEJMcps2517160?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcps2517160 Jasdeep Singh Bajwa, Gurpreet Dhaliwal, Reza Manesh, Sandesh Rao 2026-07-02 The Daily Grind This feature about treatment of appendicitis offers a case vignette accompanied by two essays, one recommending operative management and the other supporting a nonoperative approach. https://www.nejm.org/doi/full/10.1056/NEJMclde2600182?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMclde2600182 Katerina Lin, Theodore N. Pappas, Dimitrios P. Moris, David R. Flum 2026-07-02 Operative versus Nonoperative Management for Appendicitis This artificial intelligence–derived and validated machine-learning system appeared to predict the risk of Hirschsprung disease with the use of genetic and demographic data from participants in China. https://www.nejm.org/doi/full/10.1056/NEJMc2401139?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2401139 Yang Wang, Xingjie Hao, Zhonghua Yang, Allan M. Goldstein 2026-07-02 Artificial Intelligence and Detection of Hirschsprung Disease In a cluster-randomized trial involving patients having major noncardiac surgery, tranexamic acid reduced the need for red-cell transfusion during hospitalization and was noninferior to placebo for venous thromboembolism within 90 days. https://www.nejm.org/doi/full/10.1056/NEJMoa2515820?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2515820 Brett L. Houston, Daniel I. McIsaac, Rodney H. Breau, Salmaan Kanji, Peter Greenstreet, Meghan Andrews, Sinziana Avramescu, Hema S. Bagry, Robert Balshaw, Jayesh Daya, Kaitlin Duncan, Christopher C. Harle, Eric Jacobsohn, Tina Kerelska, Marshall Pitz, Paul Komenda, Sarah McIsaac, Tim Ramsay, Tarit Saha, Alan Tinmouth, Angela Recio, Daniel Szoke, Marshall Tenenbein, Sarah Slagerman, Dayna Solvason, Robert Talarico, Dean A. Fergusson, Ryan Zarychanski 2026-06-25 Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery Every year, many millions of surgical patients worldwide are unnecessarily exposed to a higher-than-necessary risk of blood transfusion because they do not receive a single dose of tranexamic acid just before the surgery. This failing is due not to a lack of high-quality scientific evidence on the overall safety, efficacy,... https://www.nejm.org/doi/full/10.1056/NEJMe2603105?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2603105 Michael F. Murphy, Ian Roberts 2026-06-25 TRACTION for Greater Surgical Use of Tranexamic Acid Among patients with traumatic hemorrhage, prehospital whole-blood transfusion was not superior to standard transfusion with red-cell and plasma components in reducing the risk of death or massive transfusion. https://www.nejm.org/doi/full/10.1056/NEJMoa2516043?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2516043 Jason E. Smith, Rebecca Cardigan, Emily Sanderson, Laura Silsby, Claire Rourke, Ed B.G. Barnard, Peter Basham, Grazia Antonacci, Richard Charlewood, Nikki Dallas, Jane Davies, Elizabeth Goodwin, Annie Hawton, Cara Hudson, Joanne Lucas, Katie Keen, Richard M. Lyon, Brodie Nolan, Gavin D. Perkins, Viona Rundell, Laura Smith, Simon J. Stanworth, Anne Weaver, Tom Woolley, Laura Green, the SWiFT Trial Group* 2026-06-18 Prehospital Whole Blood in Traumatic Hemorrhage — A Randomized Controlled Trial Among patients with moderate or severe PTS, the addition of endovascular therapy to standard care resulted in less severe PTS and better quality of life at 6 months than standard care alone but with a higher risk of bleeding. https://www.nejm.org/doi/full/10.1056/NEJMoa2519001?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2519001 Suresh Vedantham, Susan R. Kahn, William A. Marston, Ido Weinberg, Akhilesh K. Sista, Elizabeth A. Magnuson, David J. Cohen, Suman M. Wasan, Mahmood K. Razavi, Samuel Z. Goldhaber, Kristen M. Sanfilippo, Anthony J. Comerota, Ezana M. Azene, Cassius Iyad Ochoa Chaar, Daniel A. Leung, K. Pallav Kolli, Sanjeeva P. Kalva, Nassir Rostambeigi, Ajinkya Desai, Kush R. Desai, Alfonso J. Tafur, Bhavraj Khalsa, Elaine Majerus, Borong Wang, Yang Wang, Patricia Nieters, Mary Clare Derfler, Angela Oliver, Cassandra Hardy, Riyaz Bashir, Ronald Winokur, Natalie Weger, Minhaj S. Khaja, Aditya Sharma, Naganathan Mani, Pavan Kavali, Siddhant Thukral, Leslie L. Lake, Kathryn Mikkelsen, Sameer Parpia, the C-TRACT Trial Investigators* 2026-06-18 Endovascular Therapy for Post-Thrombotic Syndrome — A Randomized Trial Among patients with traumatic hemorrhage, prehospital transfusion of whole blood did not result in lower 30-day mortality than transfusion of plasma or red cells. Outcomes did not differ according to the storage age of blood. https://www.nejm.org/doi/full/10.1056/NEJMoa2602167?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2602167 Jason L. Sperry, Francis X. Guyette, Bryan A. Cotton, James F. Luther, Richard B. Utarnachitt, Matthew E. Kutcher, Brian J. Daley, Allan B. Peetz, Mayur B. Patel, Michael D. Goodman, Jeffrey A. Claridge, Nimitt Patel, Brian G. Harbrecht, Zain G. Hashmi, Ryan Zarychanski, Matthew D. Neal, Mark H. Yazer, Christian Martin-Gill, Laura E. Vincent, Ashley M. Harner, David E. Meyer, Andrew J. Latimer, Bryce R. Robinson, Catherine L. McKnight, William R. Hinckley, Keith R. Miller, Jan O. Jansen, Douglas Martin, Erin E. Fox, Bedda L. Rosario-Rivera, Stephen R. Wisniewski, the TOWAR Study Group* 2026-06-18 Prehospital Resuscitation with Type O Whole Blood for Trauma and Hemorrhage A 74-year-old man with a recent orthotopic heart transplantation was admitted to the hospital because of persistent pancytopenia that resulted in serial transfusions of packed red cells. A diagnosis was made. https://www.nejm.org/doi/full/10.1056/NEJMcpc2517867?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcpc2517867 William C. Aird, Van-Khue Ton, Sadia Sultana, Sharl S. Azar, Camille N. Kotton, Lisa D. Yuen 2026-06-18 Case 17-2026: A 74-Year-Old Man with Pancytopenia Post-thrombotic syndrome is the most common chronic complication of deep-vein thrombosis (DVT), affecting 20 to 50% of patients with DVT and causing debilitating symptoms involving the limbs — including pain, swelling, skin changes, and venous ulcers — that substantially reduce quality of life and impose considerable socioeconomic burden.1 ... https://www.nejm.org/doi/full/10.1056/NEJMe2603048?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2603048 Ronald Luiz Gomes Flumignan, Luís Carlos Uta Nakano 2026-06-18 Stenting for Post-Thrombotic Syndrome — A Step Forward Hemorrhagic shock remains the leading cause of preventable death after injury.1 Over the past two decades, early administration of blood products has transformed care for patients with bleeding. The Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial2 established that among patients with severe trauma and... https://www.nejm.org/doi/full/10.1056/NEJMe2605735?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2605735 Susan E. Rowell, Selwyn O. Rogers Jr. 2026-06-18 Prehospital Whole Blood for Traumatic Hemorrhage — Consistent Evidence from Two Randomized Trials The authors review current strategies for anticoagulation reversal in major bleeding events or urgent surgery as well as specific antidotes, limits of available evidence, thrombotic risks, unmet therapeutic needs, and ongoing research. https://www.nejm.org/doi/full/10.1056/NEJMra2506021?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMra2506021 Bianca Rocca, Hugo ten Cate 2026-06-11 Antidotes for Anticoagulation Reversal Having inherited a strong sense of professionalism from her mother and female physician mentors, a trainee finds the realities of juggling motherhood and medicine more difficult than she expected. https://www.nejm.org/doi/full/10.1056/NEJMp2513897?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2513897 Sarah Calvert 2026-06-11 Carrier HLA sensitization poses major challenges to kidney transplantation. This report describes transplantation in two highly sensitized candidates after desensitization with dual CAR T-cell therapy. https://www.nejm.org/doi/full/10.1056/NEJMoa2513428?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2513428 Vijay G. Bhoj, Mary Kaminski, Huiwu Zhao, Kyle Jackson, Wei Wang, Chengyang Liu, Robert A. Montgomery, Nicole Ali, Massimo Mangiola, Thomas R. Spitzer, Kassem Safa, Vikram Pattanayak, Raeda Taj, Joy Chiu, Thanh-Mai Bui, Elizabeth M. Sonnenberg, James F. Markmann, Michael C. Milone, Carl H. June, Don L. Siegel, Joseph A. Fraietta, Vanessa Gonzalez, Michela Locci, Matthew Palmer, Dimitri Monos, Wei-Ting Hwang, Tina Sledge, Nancy D. Bridges, Julia S. Goldstein, Jonah Odim, Stuart C. Sweet, Behdad D. Besharatian, Sabiha M. Hussain, Nicholas K. Brown, Malek Kamoun, Alfred L. Garfall, Ali Naji 2026-06-04 Brief Report: Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy In a patient with recurrent ameloblastoma, zolucatetide (formerly FOG-001) produced an ongoing partial response at 40 weeks, with resolution of solid tumor and cerebral edema. Elevated liver-enzyme levels were noted. https://www.nejm.org/doi/full/10.1056/NEJMc2517783?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2517783 Samuel J. Klempner, Moh’d Khushman, Kyriakos P. Papadopoulos, Meredith P. Pelster, Jordi A. Rodon, Rona Yaeger, Shivaani Kummar, Sunil Sharma, David Bajor, Dennis Hsu, Ranjodh S. Dhami, Bayan Alzumaili, Jeremy D. Kratz, Varun Monga, Alexander Philipovskiy, Jorge Ramos, Amber Wells, Marie H. Nguyen, Jonathan B. Hurov, Michael Cecchini 2026-06-04 Targeting of Wnt–β-Catenin Pathway in Recurrent Ameloblastoma