The New England Journal of Medicine (NEJM) RSS feed -- Search Results in Surgery. NEJM (https://www.nejm.org) is a weekly general medical journal that publishes new medical research findings, review articles, and editorial opinion on a wide variety of topics of importance to biomedical science and clinical practice. https://www.nejm.org/action/showPodcastsFeeds NEJM Group Sat, 26 Sep 2026 15:57:25 GMT 2026 NEJM Group en-us 1440 When a robust long-time patient with chronic pain and heavy alcohol use declines precipitously after a complicated hospital course, her medical team must find a way to revive her old self. https://www.nejm.org/doi/full/10.1056/NEJMp2603393?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2603393 Michael A. Incze, Laura Stolebarger 2026-09-26 The Mayor A 72-year-old man with hypertension, hyperlipidemia, and a stable ascending aortic aneurysm presented with sudden-onset, severe chest pain. CTA of the chest, abdomen, and pelvis showed a celiac-artery dissection. https://www.nejm.org/doi/full/10.1056/NEJMicm2605936?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2605936 Akshat Agrawal, Kimberly Foust 2026-09-17 Celiac-Artery Dissection Trichodysplasia spinulosa–associated polyomavirus was identified as a likely cause of neuroinvasive infection in a 16-year-old patient who had undergone renal transplantation. https://www.nejm.org/doi/full/10.1056/NEJMc2602730?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2602730 Aaron Bodansky, Natalie Pierson, Venice Servellita, Kaitlin Marquis, Robert Valdovinos, Nahid Hiermandi, Andrew W. Bollen, Ilay Caliskan, Kanish Mirchia, Charles Omura, Jessica Streithorst, Brian LaFranchi, Timothy J. Henrich, Chung-Yu Wang, Bryan Castillo-Rojas, William Bernal, Alexandra Bicki, Erica Winnicki, Marsha Lee, Kelsey Zorn, Sukhman Sidhu, Orit Glenn, Mary Karalius, Matt S. Zinter, Kendall Nash, Michael R. Wilson, Thomas M. Tarro, Joseph L. DeRisi, Charles Y. Chiu 2026-09-10 Neuroinvasive Trichodysplasia Spinulosa–Associated Polyomavirus Infection This review summarizes the management of pulmonary nodules, with an emphasis on nodule type, imaging follow-up, cancer risk, and strategies to balance timely diagnosis with avoidance of unnecessary procedures. https://www.nejm.org/doi/full/10.1056/NEJMcp2515063?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcp2515063 Matthew E.J. Callister, Gerard A. Silvestri 2026-09-03 Pulmonary Nodules Physicians’ interactions with patients and their interactions with colleagues differ far more in the United States than they do in some other countries. Could more porous boundaries improve U.S. care? https://www.nejm.org/doi/full/10.1056/NEJMp2518528?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMp2518528 Aditya S. Pawar 2026-09-03 Safe Space This video demonstrates how to insert a catheter for emergency peritoneal dialysis in adults with a technique created specifically for environments that may have limited access to resources. https://www.nejm.org/doi/full/10.1056/NEJMvcm1900723?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMvcm1900723 Sean Armstrong, Sara Dunsmore, Claudio Rigatto, Manish Sood, Paul Komenda 2026-08-20 Placement of a Catheter for Acute Peritoneal Dialysis A 31-year-old man was evaluated for an abnormal ECG. Echocardiography revealed marked ventricular hypertrophy. Subsequent imaging (shown in a video) showed near-complete apposition of the ventricular walls during systole. https://www.nejm.org/doi/full/10.1056/NEJMicm2603868?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2603868 Julian-Kai Nishizono, Marohito Nakata 2026-08-06 Obstructive Hypertrophic Cardiomyopathy The selective NaV1.8 inhibitor LTG-001 led to significantly greater reductions in pain scores than placebo over the course of 48 hours among patients who had moderate or severe pain after abdominoplasty. https://www.nejm.org/doi/full/10.1056/NEJMoa2602910?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2602910 Neil Singla, Nathaniel P. Katz, Ben Vaughn, Timothy Rogier, Todd Bertoch, Harold Minkowitz, Mallory Loflin 2026-07-30 Phase 2b Trial of a NaV1.8 Inhibitor for Acute Pain A patient with high-level HLA sensitization received T-cell engager–mediated HLA antibody depletion with teclistamab, a bispecific B-cell maturation antigen–directed CD3 T-cell engager, which enabled kidney transplantation. https://www.nejm.org/doi/full/10.1056/NEJMc2603853?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2603853 Martina Schatzl, Katharina A. Mayer, Hermine Agis, Susanne Haindl, Daniela Kriks, Gottfried Fischer, Markus Exner, Gideon Hönger, Nikolina Veljancic, Daniela M. Allmer, Irene Graf, Matthias Diebold, Philip F. Halloran, Anne Halpin, Caishun Li, Lori West, Nicolas Kozakowski, Georg A. Böhmig 2026-07-30 T-Cell Engager–Mediated HLA Antibody Depletion before Kidney Transplantation A man presented with a 2-month history of chest heaviness and a 2-week history of shortness of breath. Pulsations were visible between his ribs (shown in a video). Ultrasonography revealed a rounded structure near the heart. https://www.nejm.org/doi/full/10.1056/NEJMicm2505469?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2505469 Maithili Charan Gattu, Mehul K 2026-07-16 Descending Thoracic Aortic Aneurysm After total hip or knee arthroplasty, aspirin alone was noninferior to rivaroxaban followed by aspirin in preventing symptomatic venous thromboembolism, with a similarly low risk of bleeding complications. https://www.nejm.org/doi/full/10.1056/NEJMoa2603649?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2603649 Sudeep Shivakumar, Davide Matino, David Zukor, Susan R. Kahn, George Vincent, Raman Mundi, Pascal-Andre Vendittoli, Mohammad Refaei, Eric Bohm, Michael Tanzer, Stéphane Pelet, Glen Richardson, James Powell, Rick Ikesaka, James Douketis, Sarah Ward, Paul Kim, Stephen Mann, Susan Pleasance, Jocelyn Cormier, Pantelis Andreou, Kara Matheson, Chris Theriault, Carol West, David Anderson, Peter L. Gross, the EPCAT III Trial Investigators* 2026-07-12 Rivaroxaban Then Aspirin vs. Aspirin Alone after Total Hip or Knee Arthroplasty A 68-year-old man was evaluated in an outpatient clinic because of fatigue and dyspnea. Lung transplantation had been performed 15 months earlier. A diagnosis was made. https://www.nejm.org/doi/full/10.1056/NEJMcpc2517856?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcpc2517856 Hilary J. Goldberg, Harikrishnan Nandakumar, Brian C. Keller, Lida P. Hariri, Arthur Y. Kim, Briana N. Castillo 2026-07-09 Case 19-2026: A 68-Year-Old Man with Fatigue, Fever, and Hypoxemia Growing acceptance of voluntary euthanasia, which opens the door to death by organ donation, warrants a recontextualization of the dead donor rule and assessment of the ethical principles involved. https://www.nejm.org/doi/full/10.1056/NEJMms2601611?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMms2601611 Carter Winberg, Ian Ball, Robert D. Truog 2026-07-09 Contextualizing the Dead Donor Rule in an Era of Voluntary Euthanasia A 71-year-old man was found to have a tapeworm (shown in a video) in his peritoneal cavity during elective repair of a right inguinal hernia. He recalled having consumed raw snake meat during his military service 50 years earlier. https://www.nejm.org/doi/full/10.1056/NEJMicm2603440?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMicm2603440 Chang-Seop Lee, Yeon Jun Jeong 2026-07-09 Sparganosis A 56-year-old woman was hospitalized with gait instability. Eight weeks earlier, she had noticed ascending symmetric sensations of painful “pins and needles” that had begun in her feet; she later had memory impairment and irritability. https://www.nejm.org/doi/full/10.1056/NEJMcps2517160?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMcps2517160 Jasdeep Singh Bajwa, Gurpreet Dhaliwal, Reza Manesh, Sandesh Rao 2026-07-02 The Daily Grind This feature about treatment of appendicitis offers a case vignette accompanied by two essays, one recommending operative management and the other supporting a nonoperative approach. https://www.nejm.org/doi/full/10.1056/NEJMclde2600182?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMclde2600182 Katerina Lin, Theodore N. Pappas, Dimitrios P. Moris, David R. Flum 2026-07-02 Operative versus Nonoperative Management for Appendicitis This artificial intelligence–derived and validated machine-learning system appeared to predict the risk of Hirschsprung disease with the use of genetic and demographic data from participants in China. https://www.nejm.org/doi/full/10.1056/NEJMc2401139?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMc2401139 Yang Wang, Xingjie Hao, Zhonghua Yang, Allan M. Goldstein 2026-07-02 Artificial Intelligence and Detection of Hirschsprung Disease In a cluster-randomized trial involving patients having major noncardiac surgery, tranexamic acid reduced the need for red-cell transfusion during hospitalization and was noninferior to placebo for venous thromboembolism within 90 days. https://www.nejm.org/doi/full/10.1056/NEJMoa2515820?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2515820 Brett L. Houston, Daniel I. McIsaac, Rodney H. Breau, Salmaan Kanji, Peter Greenstreet, Meghan Andrews, Sinziana Avramescu, Hema S. Bagry, Robert Balshaw, Jayesh Daya, Kaitlin Duncan, Christopher C. Harle, Eric Jacobsohn, Tina Kerelska, Marshall Pitz, Paul Komenda, Sarah McIsaac, Tim Ramsay, Tarit Saha, Alan Tinmouth, Angela Recio, Daniel Szoke, Marshall Tenenbein, Sarah Slagerman, Dayna Solvason, Robert Talarico, Dean A. Fergusson, Ryan Zarychanski 2026-06-25 Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery Every year, many millions of surgical patients worldwide are unnecessarily exposed to a higher-than-necessary risk of blood transfusion because they do not receive a single dose of tranexamic acid just before the surgery. This failing is due not to a lack of high-quality scientific evidence on the overall safety, efficacy,... https://www.nejm.org/doi/full/10.1056/NEJMe2603105?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMe2603105 Michael F. Murphy, Ian Roberts 2026-06-25 TRACTION for Greater Surgical Use of Tranexamic Acid Among patients with traumatic hemorrhage, prehospital whole-blood transfusion was not superior to standard transfusion with red-cell and plasma components in reducing the risk of death or massive transfusion. https://www.nejm.org/doi/full/10.1056/NEJMoa2516043?rss=searchAndBrowse https://www.nejm.org/doi/full/10.1056/NEJMoa2516043 Jason E. Smith, Rebecca Cardigan, Emily Sanderson, Laura Silsby, Claire Rourke, Ed B.G. Barnard, Peter Basham, Grazia Antonacci, Richard Charlewood, Nikki Dallas, Jane Davies, Elizabeth Goodwin, Annie Hawton, Cara Hudson, Joanne Lucas, Katie Keen, Richard M. Lyon, Brodie Nolan, Gavin D. Perkins, Viona Rundell, Laura Smith, Simon J. Stanworth, Anne Weaver, Tom Woolley, Laura Green, the SWiFT Trial Group* 2026-06-18 Prehospital Whole Blood in Traumatic Hemorrhage — A Randomized Controlled Trial